王晓晖,博士
助理研究员
联系方式:010-6428 6180;wangxhui2014@163.com
个人简历
1981年4月出生于山东省潍坊市
2000年09月-2004年07月:中国农业大学农学与生物技术学院学士
2005年09月-2012年01月:中国农业大学生物学院,博士
2012年07月至今:北京中医药大学中药现代研究中心,助理研究员
研究领域
中药植物分子生物学及生物合成
代表论著(限10篇)
1. Xiaohui Wang, Bowen Gao, Xiao Liu, Xianjuan Dong, Zhongxiu Zhang, Huiyan Fan, Le Zhang, Juan Wang, Shepo Shi*, Pengfei Tu*. Salinity stress induces the production of 2-(2-phenylethyl)chromones and regulates novel classes of responsive genes involved in signal transduction in Aquilaria sinensis calli. BMC plant biology,2016,16(1): 119.
2. Juan Wang, Xiaohui Wang, Xiao Liu, Jun Li, Xiaoping Shi, Yuelin Song, Kewu Zeng, Le Zhang, Pengfei Tu*, and Shepo Shi*. Synthesis of Unnatural 2-Substituted Quinolones and 1,3-Diketones by a Member of Type III Polyketide Synthases from Huperzia serrata. Organic Letters, 2016,18(5): 3550-3553.
3. Zhongxiu Zhang, Xiaohui Wang, Wangqing Yang, Juan Wang, Cong Su, Xiao Liu, Jun Li, Yunfang Zhao, Shepo Shi*, Pengfei Tu*. Five 2-(2-Phenylethyl)chromones from Sodium Chloride-Elicited Aquilaria sinensis Cell Suspension Cultures. Molecules.2016. 21(5): E555.
4. Bowen Gao,Xiaohui Wang,Xiao Liu ,Shepo Shi *,PengfeiTu *. Rapid preparation of (methyl)malonyl coenzyme A and enzymatic formation of unusual polyketides by type III polyketide synthase from Aquilaria sinensis,Bioorganic & Medicinal Chemistry Letters,2015,25(6):1279-1283。
5. Le Zhang, Bowen Gao, Xiaohui Wang, Zhongxiu Zhang, Xiao Liu, Juan Wang, Ting Mo, Yuyu Liu, Shepo Shi*, Pengfei Tu. Identification of a new curcumin synthase from ginger and construction of a curcuminoidproducing unnatural fusion protein diketide-CoA synthase::curcumin synthase. RSC Advances. 2016. 15(6): 12519-12524.
6.Ting Mo, Xiao Liu, Yuyu Liu, Xiaohui Wang, Le Zhang, Juan Wang, Zhongxiu Zhang, Shepo Shi*, Pengfei Tu * Expanded investigations of the aglycon promiscuity and catalysis characteristic of flavonol 3-O-rhamnosyltransferase AtUGT78D1 from Arabidopsis thaliana. RSC Advances. 2016, 6(88): 84616-84626
7. 董先娟,刘晓,张钟秀,张乐,王娟, 屠鹏飞,王晓晖*,史社坡*; 白木香两个小分子热激蛋白基因(sHSPs)的克隆及表达分析。中草药, 2016,47(22)4054-4061.
8. 王晓晖,刘晓,高博闻,张钟秀,史社坡,屠鹏飞;腊梅葡萄糖-6-磷酸脱氢酶(G6PDH1)基因的克隆及表达分析。中国中药杂志,2015,40(21):4160-4164.
9. Xiaohui Wang,Yanjing Zhang,Jin Xu,LinDan Shi,HuiYan Fan,ChengguiHan,Dawei Li,Jialin Yu*. The R-rich motif of Beet black scorch virus P7a movement protein is important for the nuclear localization,nucleolar targeting and viral infectivity,Virus Research,2012,167(2):207-218。
科研项目
1. 诱导细胞凋亡蛋白MAPK3和MAPKK5对白木香2-苯乙基色酮生物合成的调控机制及生物学功能研究,国家自然科学基金青年科学基金项目(81503182),主持, 2016.01-2018.12.
2. 白木香查尔酮合成酶的生物学功能和体外生物合成研究, 北京市自然科学基金青年科学基金项目 (7154216), 主持,2015.01-2016.12
3. 蛋白激酶C在白木香结香过程中的功能分析,北京中医药大学“青年教师专项计划项目”,主持,2014.01-2014.12.